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Screening for Cancer

Providers should screen individuals for cancer in body parts that are part of sexual and reproductive anatomy. Screening recommendations by type of cancer can be found in Exhibit 13.

Exhibit 13. Cancer Screening Recommendations by Type of Cancer, for People of Reproductive Age

Type of cancerAge, yearsScreening recommendationsSource
Breast163< 40No screeningUSPSTF
 40–74Mammography bienniallyUSPSTF
Persons with BRCA mutations or increased risk of breast cancer16425Persons with BRCA1 or BRCA2 mutations should receive a clinical breast exam every six to 12 months and annual breast imaging starting at age 25. ACOG
Cervix165< 21No screeningUSPSTF
 21–29Screen every three years with cytology alone.USPSTF
 > 30Screen with a co-test (cytology and hrHPV testing) every five years, hrHPV testing alone every five years, or cytology every three years.USPSTF
Anus166> 35

Screen adults at higher risk who are age 35 and older, with screening initiated no later than age 45, with digital anal rectal examination (DARE) or anal cytology and/or hrHPV testing with DARE:

  • People living with HIV
  • Non-HIV immunosuppressed
  • Men who have sex with men
  • Transgender women
  • History of vulvar high-grade squamous intraepithelial lesion (HSIL) or cancer
  • Other groups with high incidence
Evidence Review
Oropharynx167 Screen annually with dental examination.USPSTF
Penis and scrotum166 Screen individuals with a history of anogenital HSIL or cancer by visually inspecting the penis and scrotum.Evidence Review
Testicular168, 16915–55Testicular self-exam is not currently recommended by USPSTF. Testicular exam at routine physicals can be a decision between patient and provider. Providers can encourage patients to be familiar with their testicles.USPSTF

Resources for Providers

Source:
U.S Preventive Services Task Force
Source:
American Society for Colposcopy and Cervical Pathology
Source:
Clinical Training Center for Sexual and Reproductive Health